Abstract
Background and Aims : Lipids play a major role in atherosclerosis and are therefore potential biomarker targets. Investigating the spatial distribution of lipids in plaques can aid in understanding the role of lipids in local pathobiology, plaque progression and subsequent biomarker discovery. In contrast to histology, mass spectrometry imaging (MSI) can visualize the spatial distribution of a wide variety of lipid species in human carotid plaques.
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