Abstract
One of the most distinctive characteristics of chromatin remodeling during spermatogenesis is the expression of a large number of histone variants with complex modification forms. In addition to all the somatic-type histone variants, spermatogenic cells express testis-specific histones corresponding to three of the four core histones. To understand the global dynamics of chromatin structure and function during spermatogenesis, comprehensive analys es of how histone variants incorporate into the nucleosome and their covalent modifications are required.
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