Abstract
The marine environment is a rich source of bioactive small peptides. The toxic marine creatures could produce a large number of small toxic neuropeptides consisting of several intra-molecular disulfide bridges. The neuropeptides from ocean surprise researchers with their abilities to discriminate different subtypes of their molecular targets or ion channels, which makes them not only effective tools for neuroscience research but also promising molecular model of drug design or therapeutic agent. The representative neuropeptides are sea anemone toxins, conotoxins, sea snake toxins, jellyfish toxins, venomous fish toxins and stingrays toxins. In this article, we reviewed the progress in the studies on marine peptide toxins and the potential use in the neuroscience research and drug design.
Published Version
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