Marine Natural Products from Marine Sponge Microorganisms

Abstract

Marine sponge microorganisms were a kind of important source for marine natural products (MNPs) due to their chemodiversity and good biological activities. They account for 19% MNPs of marine fungal origins from 1951 to 2014. This paper reviewed the sources, structures, and bioactivities of 519 sponge microbial MNPs reported in 1988 to the end of 2014. These new MNPs have a variety of chemical structures including nitrogen compounds, steroids and terpenoids, polyketides, and so on. The half, of MNPs from marine sponge microorganisms, which are biological activities and the major bioactivities are, antimicrobial activity and cytotoxicity.