Abstract
Silber underscores the importance of urine toxicology for detection of recent cannabinoid use by adolescent patients. Because Δ9-THC, the major psychoactive component of cannabis, is lipophilic, it is stored in adipose tissue and released slowly and unevenly back into the bloodstream during the 21 days or more after use. 9-Carboxy-tetrahydrocannabinol (THC), a stable nonpsychoactive metabolite of cannabis, is excreted in relatively large amounts in feces (70%) and urine (30%) and can be detected by urine toxicology for several days after last use of marijuana or hashish.
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