Abstract
Background and aim: Reclaiming fatty livers for transplantation could decrease donor shortage. We demonstrated that obese Zucker rat livers were damaged by cold-storage and better preserved by sub-normothermic machine perfusion (Vairetti et al., 2009). We presently evaluate the model of steatosis induced by Methionine-Choline deficient diet (MCD) in rat liver, respect to an isocaloric diet (control group). We report in situ, biochemical and molecular indices of oxidative stress.
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