Abstract
The nanoscale magnetic configuration of self-assembled groups of magnetite 40 nm cubic nanoparticles has been investigated by means of electron holography in the transmission electron microscope (TEM). The arrangement of the cubes in the form of chains driven by the alignment of their dipoles of single nanocubes is assessed by the measured in-plane magnetic induction maps, in good agreement with theoretical calculations.
Highlights
Magnetic hyperthermia has been the subject of intense research in recent years
The thermal stability gained by creating arrays, shown by simulations of magnetic response versus temperature, is an advantage when exploiting hysteresis losses. These results indicate a promising way to increase the hyperthermia performance by assembling cubic particles in elongated chains
We were able to map the magnetic configuration of ensembles of Fe3O4 nanocubes, approximately 40 nm in size, by means of electron holography
Summary
It allows for a complementary approach to standard therapies for cancer treatment (for review, see e.g., [1]). This technique offers the advantage of delivering a highly localized damage via the targeting of tumor cells with magnetic nanoparticles. By exciting these nanoparticles with a radio-frequency signal, local heating of the surrounding area is achieved, with lower full-system toxicity than chemotherapy and without ionizing radiation affecting healthy tissue, as in the case of radiotherapy. Improving efficiency by optimizing the magnetic response of nanoparticles is crucial in order to obtain therapeutic effects while keeping the number of nanoparticles as low as possible
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
