Manufacturing and formulation of natural products based on the Chitosan as active ingredientin the forms of gel and spray

Abstract

The purpose of this work is to make based on natural polysaccharide compounds such as chitosan for the microorganism testwhich led to the destruction of Escherichia coli bacteria, Candida albicans vegetative cells and Aspergillus niger spores and Herpes simplex virus (HSV-1). Chitosan products in the forms of gel and spray have bactericidal, fungicidal and virucidal properties as antiseptic products. Chitosan polysaccharides with high molecular weight are extracted from aquatic organisms such as shrimp.Physical and chemical analysis, identification test of Chitosan as active ingredient and also non-sensitizing test of these products in the forms of gel and spray have been done on the rabbit's skin that did not show no sensitivity and inflammation. It seems that natural products in the forms of gels and sprays based on chitosan, as alternative products for alcohol and chemical compounds, have a useful and promising role as antiseptic in eliminating bacteria, fungi and viruses left on the skin of the hands.