Abstract

A bioactive calcium sulfate/glass composite was prepared using a sintering technique, and Ca–P–Si glass particles were prepared by spray pyrolysis. The glass exhibited bioactivity in terms of its ability to form apatite in a simulated body fluid. The glass was transformed into two crystallized phases, i.e., calcium phosphate and calcium silicate, respectively, during the heating stage. The presence of the crystallized phases retarded the densification of calcium sulfate. A high sintering temperature of 1200 °C was needed to prepare the composite. The increased addition of glass enhanced the strength and decreases the degradation rate of calcium sulfate. The new composite is not only degradable but also bioactive.

Highlights

  • Autografts exhibit better biocompatibility com‐ pared to synthetic bioceramics, degradable bioceramics serve as alternatives for patients who want to avoid undergo‐ ing further donor site injury

  • The slow degradation rate of the bioactive glass graft leads to a decreased amount of bone formation due to its continued presence

  • Spherical glass particles are prepared by spray pyrolysis (Fig. 1), which first generates liquid drops, lead‐ ing to the formation of spherical particles after pyrolysis at 700 °C

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Summary

Introduction

Autografts exhibit better biocompatibility com‐ pared to synthetic bioceramics, degradable bioceramics serve as alternatives for patients who want to avoid undergo‐ ing further donor site injury. By releasing calcium ions after implantation, these degradable bioceramics aid in the recovery of bone defects (Rahaman et al 2011). Among these bioceramics, calcium sulfate and bioactive glass exhibit several desirable biological properties Calcium sulfate and bioactive glass exhibit several desirable biological properties The combination of these two bioceramics has attracted attention previously. Silveira et al (2008) have applied calcium sulfate as a barrier for bio‐ active glass. This combination exhibits a better osteoconduc‐ tivity: 24% bone formation in the central region is observed,

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