Management of Xerostomia and Hyposalivation in Hypertensive Patient's Using Candesartan Cilexetil

Abstract

Saliva’s disorder and dry mouth (xerostomia) are related to routine medication as antihypertensives. Candrsartan cilexetil is an angiotensin receptor blocker (ARB) hypertension drug that indirectly affects saliva by changing fluid and electrolyte balance. To examine the management of xerostomia and hyposalivation in hypertensive patients due to use of candesartan cilexetil. A 70 year old female patient complained her mouth felt dry since 1 year ago when she was diagnosed with hypertension. The patient consumes candesartan cilexetil once daily, 8 mg. Intra oral showed were edentulous areas on the entire upper and lower jaw with the patient's oral mucosa being dry, saliva thick, sticky and frothy. In this case, saliva’s rate measurement showed a result of 0.16 mL/minute. After intervention using dry mouth gel for two weeks, a saliva rate of 0.38 mL/minute. During the control, patient didn’t complaining dry mouth. This is accordance with the literature, dry mouth gel can improve signs and symptoms of dry mouth and increase the patient's ability to swallow. Patient’s take antihypertensive drugs have manifestations in form of xerostomia. The treatment carried out to improve the condition of patient's oral cavity is providing education on maintaining healthy teeth and mouth as well as using dry mouth gel applied to the entire oral mucosa. In this case, an increase salivary rate from 0.16 mL/minute to 0.38 mL/minute. The concluded, use of dry mouth gel is effective in treating xerostomia and can increase the rate of saliva in the oral cavity