Management of large peripheral nerve defects with autografting

Abstract

Listen

Translate article

IntroductionA segmental nerve defect from trauma results in significant loss of function of the extremity, and rarely occurs in isolation. Autografting of the nerve defect is the current gold standard. MethodsA review of the recent literature regarding peripheral nerve defects after trauma treated with autograft. ResultsIdentification of the zone of nerve injury is difficult and appropriate resection is critical for good outcomes. Meaningful recovery is more likely with application of excellent technique. Many of the factors affecting outcomes are not modifiable. ConclusionNerve grafting for segmental nerve injuries continues to be an essential and appropriate treatment.