Abstract

Background: Generalized Anxiety Disorder (GAD) is a common mental health condition characterized by persistent and excessive worry or anxiety about various aspects of life, such as work, relationships, and daily activities. Anxiety disorders can result in work and school absences, posing a greater financial burden compared to other psychiatric disorders, given their higher global prevalence of approximately 642 million individuals affected. Although effective psychological treatments like Cognitive-Behavioral Therapy and mindfulness-based therapies exist for GAD, accessibility remains an issue for many. Common medications, including Selective Serotonin Reuptake Inhibitors and Benzodiazepines, carry potential side effects. While there has been some exploration of Homoeopathy's effectiveness in GAD, comprehensive discussions on the approach and posology are lacking. Case summary: A 52-year-old female patient, exhibiting symptoms of generalized anxiety coupled with severe autonomic symptoms, was diagnosed with GAD based on DSM-5 criteria. The cases were systematically analyzed and treated with individualized homeopathic medicines in fifty millesimal potencies. The approach involved initial blood tests and thyroid function assessments to rule out systemic illnesses. Thorough case assessments were conducted using standardized record forms and the Kentian method to compile a comprehensive symptom profile. Following symptom analysis, RADAR Opus software was used for repertorization, leading to the prescription of Pulsatilla in 0/1 potency, determined by repertorial totality and final consultation with materia medica. Baseline severity and progress were assessed monthly using the Hamilton Anxiety Scale (HAM-A), while the World Health Organization Quality of Life brief version (WHO QOL BREF) was administered every six months. HAM-A scores, starting at 45, decreased to 3 at the end of the one-year observation period. The Modified Naranjo Criteria for Homeopathy—Causal Attribution Inventory was utilized to establish a causal relationship between Homoeopathic intervention and outcomes. Conclusion: These findings provide preliminary evidence supporting the potential utility of fifty millesimal potencies of individualized homeopathic medicines in managing GAD. They underscore the need for further research in this area.

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