Abstract
Background: Surgical site infections (SSIs) remain among the most frequent complications of surgery. Surgery is the mainstay of treatment in the majority of cases, but antimicrobial therapy is required for some indications Methods: Selective review of the literature to provide an up-to-date overview of the diagnostic criteria and different treatment options pertaining to the various forms of SSIs. Only articles published in English and listed in MEDLINE/PubMed were reviewed. Special attention was given to antimicrobial chemotherapy of established SSIs Results: Following a consensus meeting in 1992, SSIs were categorized by the U.S. Centers for Disease Control and Prevention (CDC) into superficial and deep incisional and organ/space types. Whereas superficial SSIs usually require only opening and drainage of the incision, deep incisional SSIs require urgent surgical debridement and usually necessitate antibiotic therapy. Vacuum-assisted closure of open wounds is promoted for a variety of indications, but l...
Published Version
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