Abstract
ntroduction: Osteonecrosis of the jaws is ften related to either radiation or bisphoshonate treatment. Rarely, osteonecrosis is elated to viral infections. Objective: To report four patients with erpes Zoster related osteonecrosis in the aws. Materials and methods: The patient aterial comprised one man and three omen, mean age 52 years. The patients ere examined clinically and radiologially, and osteonecrosis was treated. The oster infection involved the maxillary ranch of the trigeminal nerve in three ases and the mandibular branch in one ase, and led to loss of teeth in three cases. he onset of osteonecrosis was spontaeous (1 case), related to tooth extractions 2 cases) and related to attempted bone augentation and implant insertion (1 case). everal attempts by an experienced oral urgeon to perform bone augmentation and mplant insertion failed. The follow-up time was 7, 17, 20, and 0+ months, respectively. All patients had o sign of osteonecrosis at final examiation, and all had removable dentures to eplace the missing teeth. Summary: This report shows that Heres Zoster infection in the maxillary and andibular branches of the trigeminal erve may be associated with signifiant morbidity including loss of teeth, steonecrosis and potential problems with mplant treatment. Conclusions: A working hypothesis as postulated thatHerpes Zoster infection nvolving the jawsmay lead to either immediate or late osteonecrosis, to be tested in a prospective trial. Triggering factors are tooth extractions or other surgery. It is advised to include previous Herpes Zoster infection in the medical history questionnaire. Conflict of interest: None declared.
Published Version
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