Abstract
Primary eosinophilic gastrointestinal disorders (EGIDs) are emerging chronic/remittent inflammatory diseases of unknown etiology, which may involve any part of the gastrointestinal (GI) tract, in the absence of secondary causes of GI eosinophilia. Eosinophilic esophagitis is the prototype of eosinophilic gastrointestinal disorders and is clinically characterized by symptoms related to esophageal inflammation and dysfunction. A few studies have assessed the nutritional status of patients with eosinophilic gastrointestinal disorders, showing conflicting results. This review summarizes the current evidence on the nutritional status of patients with EGIDs, focusing on the pediatric point of view and also speculating potential etiological mechanisms.
Highlights
Olivero, F.; Raffaele, A.; Cereda, E.; Pediatric Clinic, Department of Pediatrics, Fondazione IRCSS-Policlinico San Matteo, University of Pavia, Pediatric Surgery Unit, Department of Maternal and Child Health, Fondazione IRCCS Policlinico San Matteo, Clinical Nutrition and Dietetics Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy; Immuno-Allergology Laboratory of the Clinical Chemistry Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
This review aims to summarize the current evidence on the nutritional status and disease (GERD)
A few studies have assessed the role of body weight and body mass index (BMI) in children and adolescents with eosinophilic esophagitis (EoE), and no articles were published on eosinophilic gastrointestinal disorders (EGIDs) distal to the esophagus (Table 2)
Summary
Obesity is a global public health problem associated with many chronic diseases, including type 2 diabetes, arterial hypertension, cardiovascular diseases, and asthma [12]. Growing evidence supports the association between obesity and immune disorders, such as cancer, autoimmunity, and atopy [13]. Data from the National Health and Nutrition Examination Study III (NHANES III) have described a positive association between body mass index (BMI) and atopy rates [17]. A few studies have assessed the role of body weight and BMI in children and adolescents with EoE, and no articles were published on EGIDs distal to the esophagus (Table 2). There is evidence that most adults with EoE mainly have a good nutritional status and expected BMI values [19,20,21,22,23,24,25,26,27]. Children with GERD and EoE had a weight-for-length (WFL) Z score at the 18th–13th percentiles; they did not meet the criteria for failure to thrive (FTT) [24]
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call