Abstract
Sacrococcygeal teratoma (SCT) is a common congenital neoplasm, contains derivatives of more than one of the three embryonic germ cell layers. However, malignant Sacrococcygeal Yolk Sac tumor (YST) is an extremely rare extra-gonadal germ cell tumor. This case describes a two and half years old female child presenting with history of swelling at sacrococcygeal region for nine months. Case was evaluated clinically. Patient’s serum alpha fetoprotein (AFP) level was elevated abnormally. FNAC of the swelling was done which shows suspicious cell for immature teratoma. Swelling excised and histopathological examination was carried out, the report of which shows malignant sacrococcygeal teratoma with yolk sac tumor.
Highlights
Among the Germ Cell Tumors (GCT), Sacrococcygeal teratoma (SCT) is the most common congenital neoplasm occurring with a frequency of 1 in 20,000 to 40,000 live births [1] [2], it is seen in adults [3]
Malignancy is usually limited to a single element, a yolk sac tumor (YST), known as endodermal sinus tumor
Most germ cell tumors (GCT) in children originate in the gonads, the most common primary site for YST is the sacrococcygeal region [4]
Summary
Among the Germ Cell Tumors (GCT), Sacrococcygeal teratoma (SCT) is the most common congenital neoplasm occurring with a frequency of 1 in 20,000 to 40,000 live births [1] [2], it is seen in adults [3]. These tumors are predominantly seen in females in a ratio of 4:1 and approximately 80% of the affected infants are female [4]. We present a case of a two and half year old female child with malignant SCT with YST that developed before two years of her age and it was type IV SCT in anatomic location
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