Abstract
A 20-year-old man who presented with a metastatic lesion in his left humerus was found to have a malignant chemodectoma arising in the superior mediastinum. Analysis of urinary phenolic acid excretion revealed a marked increase in homovanillic acid, a slight increase in vanillyl mandelic acid, and normal total metanephrine excretion. The demonstration of secretory granules by electron microscopy suggests that the tumor was responsible for the secretion of catecholamines or catecholamine metabolites.
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