Abstract
Background: Malaria infection during pregnancy is a major public health problem in tropical and subtropical regions globally. Anaemia is often an adverse outcome of severe parasitic infections during pregnancy in developing countries. Pregnant women in malaria-endemic communities are more susceptible to Plasmodium falciparum infections than non-pregnant women of child-bearing age. Objective: To comparatively investigate malaria and anaemia in pregnant and non-pregnant women of child-bearing age. Design: A cross-sectional comparative study. Three hundred and eighty pregnant women and 380 non-pregnant women were screened for the study. Setting: The study was conducted at the University Hospital, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. Measurements: Participants’ demographic data were collected via the administration of questionnaires. In addition their blood samples were analyzed for haemoglobin level and malaria parasites, while stool samples from the pregnant women were examined for intestinal parasites. Results: The study revealed that pregnant women have higher malaria parasitaemia (12.6%) and anaemia (62.6%). The species of Plasmodium isolated from the pregnant women were P. falciparum (85.4%), P. malariae (4.2%) and P. ovale (10.4%). Malaria parasitaemia was higher in the primigravidae (14%). However multigravidae recorded the highest anaemia prevalence (67.1%). Age of pregnant women was a factor affecting malaria parasitaemia with a significant P-value and OR (P value = 0.0041, 0R = 7.61). Conclusions: Pregnant women were more susceptible to malaria and anaemia than non-pregnant women of child-bearing age. Most of the pregnant women reported at antenatal clinic during the second trimester. Primigravidae however recorded the highest malaria parasitaemia. The main species of Plasmodium observed in the blood samples was falciparum.
Highlights
Malaria is a serious public health problem in pregnant women in the tropics [1]
Pregnant women were more susceptible to malaria and anaemia than non-pregnant women of child-bearing age
This study focused on investigating comparatively malaria and anaemia, and the associated risk factors, among pregnant women and non-pregnant women of child-bearing age at the University Hospital, Kwame Nkrumah University of Science and Technology, Ghana
Summary
Malaria is a serious public health problem in pregnant women in the tropics [1]. Plasmodium falciparum is responsible for the majority of malaria infections. Pregnant women in malaria-endemic communities are more susceptible to Plasmodium falciparum infections than non-pregnant women of child-bearing age. Objective: To comparatively investigate malaria and anaemia in pregnant and non-pregnant women of child-bearing age. Measurements: Participants’ demographic data were collected via the administration of questionnaires In addition their blood samples were analyzed for haemoglobin level and malaria parasites, while stool samples from the pregnant women were examined for intestinal parasites. Results: The study revealed that pregnant women have higher malaria parasitaemia (12.6%) and anaemia (62.6%). The species of Plasmodium isolated from the pregnant women were P. falciparum (85.4%), P. malariae (4.2%) and P. ovale (10.4%). Conclusions: Pregnant women were more susceptible to malaria and anaemia than non-pregnant women of child-bearing age. The main species of Plasmodium observed in the blood samples was falciparum
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