Abstract
Objective: To determine the main microbial genotypes and their antimicrobial resistance and susceptibility profile commonly used in the treatment of oncologic patients with febrile neutropenia, carried out through the review of the clinical histories of the patients’ medical records at the Hospital do Cancer de Muriae-Fundacao Cristiano Varella. Methods: Quantitative research, determined the susceptibility profile of microorganisms in patients with febrile neutropenia from April 2007 to April 2008 by reviewing clinical histories of patients’ medical records at the referred hospital. Results: Of the total of 8 patients evaluated with Gram-negative microorganisms, 50% of the patients were female and 50% were male. Of the 18 patients evaluated with Gram-positive microorganisms 66% were female and 34% male. Gram-positive bacteria are prevalent and cause around 60% of documented bacteremias, although Gram-negative bacteria are more common in febrile neutropenic patientes. Conclusion: Exaggerated use of antimicrobials in hospitalized patients leads to the suppression of drug-sensitive microorganisms from the intestinal flora and promotes the persistence and growth of resistant bacteria. The antibiotic should be used in a curative manner with other therapeutic measures with the determined bacterial infection.
Highlights
The main factors that increase environmental carcinogens or allow for a longer and longer exposure of humans to these agents, contributing to the increase in the incidence of cancer, are the urbanization, industrialization and life expectancy of the population [1].Cancer is one of the causes of increased mortality and morbidity in the world, with more than ten million new cases and more than six million deaths per year
To determine the main microbial genotypes and their antimicrobial resistance and susceptibility profile commonly used in the treatment of oncologic patients with febrile neutropenia, carried out through the review of the clinical histories of the patients’ medical records at the Hospital do Câncer de Muriaé-Fundação Cristiano Varella
Of the 18 patients evaluated with Gram-positive microorganisms 66% were female and 34% male
Summary
The main factors that increase environmental carcinogens or allow for a longer and longer exposure of humans to these agents, contributing to the increase in the incidence of cancer, are the urbanization, industrialization and life expectancy of the population [1].Cancer is one of the causes of increased mortality and morbidity in the world, with more than ten million new cases and more than six million deaths per year. The number of cancer cases has increased considerably, especially since the last century, and is one of the most important public health problems in the world. In these circumstances, it has already been considered an acute and invariably fatal disease, and is one of the main causes of death in Brazil [2]. It has already been considered an acute and invariably fatal disease, and is one of the main causes of death in Brazil [2] Today it is considered a chronic disease, with prospects of cure in most cases. Diagnosis is a stressful time and the chemotherapy protocols used in the treatment, they offer a variety of medical care, do not contemplate the patient and his/her relatives in the discovery and confrontation of the diagnosis, causing pain to the patient [3]
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