Abstract
The motion of functionalized superparamagnetic beads provides the foundation for the manipulation of labelled chemical and biological species in microfluidic environments, where patterned ferromagnetic thin films serve as a versatile and reconfigurable platform for biomedical applications. A recurring release and capture of superparamagnetic microbeads is achieved by moving stray magnetic field gradients generated by a circulating micromagnetic state of a soft magnetic disc. The full micromagnetic analysis of the transport dynamics fully describes the fundamental alternating behaviour of microsphere motion. An excellent level of agreement is obtained between experiment and modelling for all stages of motion, confirming the validity of describing particle motion dynamics in the applied quasi ab initio modelling approach. The demonstrated comprehension of the non-linear microbead displacement opens the way towards the modelling of various alternative dynamic excitation schemes, even for complicated integrated micromagnetic platforms, for controlled biological analyte–superparamagnetic bead manipulation.
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