Abstract
Multilayered [FeNi (100 nm)/Cu (3 nm)]5/Cu (500 nm)/[Cu (3 nm)/[FeNi (100 nm)]5 structures were used as sensitive elements of the magnetoimpedance (MI) sensor prototype for model experiments of the detection of magnetic particles in blood vessel. Non-ferromagnetic cylindrical polymer rod with a small magnetic inclusion was used as a sample mimicking thrombus in a blood vessel. The polymer rod was made of epoxy resin with an inclusion of an epoxy composite containing 30% weight fraction of commercial magnetite microparticles. The position of the magnetic inclusion mimicking thrombus in the blood vessel was detected by the measurements of the stray magnetic fields of microparticles using MI element. Changes of the MI ratio in the presence of composite can be characterized by the shift and the decrease of the maximum value of the MI. We were able to detect the position of the magnetic composite sample mimicking thrombus in blood vessels. Comsol modeling was successfully used for the analysis of the obtained experimental results and the understanding of the origin the MI sensitivity in proposed configuration. We describe possible applications of studied configuration of MI detection for biomedical applications in the field of thrombus state evaluation and therapy.
Highlights
IntroductionPublisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations
(100 nm)]5 MI sensitive element measured along easy magnetization axis (EMA) and hard magnetization axis (HMA)
The shapes of the hysteresis loops are in accordance with magnetic domain structures and special features of magnetization processes for magnetization along EMA and HMA
Summary
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. Nanostructured magnetic materials have become a subject of interest in the last decades. In many senses, their popularity is based on the development of new fabrication techniques and significant improvements of existing synthesis methods [1,2,3]. Their popularity is based on the development of new fabrication techniques and significant improvements of existing synthesis methods [1,2,3] They attract special attention from both the point of view fundamental physical and chemical properties and variety of practical applications [3,4,5]. Among other systems magnetic nanoparticles were in focus for their investigation in technical devices [6,7,8] and medical conditions [9,10]
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