Abstract
Since the appearance of magneto-biology as an intriguing field of Big Biology, the most significant event, which was happened in it, was the discovery of huge isotope effects, when natural magnesium, calcium and zinc ions in the catalytic sites of enzymes were replaced with nuclear spin magnetic ions 25Mg2+, 43Ca2+, and 67Zn2+ of their stable isotopes. This discovery elucidated physical sense and the origin of numerous magneto-biological effects; it has illuminated all magneto-biology and introduced it as a respectable science. Now the spin concept and radical pair mechanism are generally accepted and overwhelmingly used to interpret experimentally detected magneto-biological effects. In terms of the radical pair mechanism the DNA repair, Hayflick limit and biological longevity under magnetic control are discussed. It is emphasized that magneto-biology is a means to better understand Big Biology itself.
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