Magnetization transfer contrast imaging (MTC): its fundamentals, technics and applications

Abstract

Using magnetisation transfer (MTC), a new contrast could be achieved on magnetic resonance images (MRI). Two different techniques are available to produce MTC: on- and off-resonance technique. Basic physics of MTC and the two techniques are extensively described in this review article. Potential advantages in using MTC are imaging of cartilage, multiple sclerosis and MR angiography. Particularly the detection of contrast media enhancing brain lesions were improved using MTC. Early cartilage degeneration could be visualised with improved contrast on MTC images. This article gives an overview of potential and accepted applications.