Abstract
The incorporation of magnetic and upconversion luminescent properties into one single nanostructure is highly desirable in nanomedicine for contrast agents and/or nanotheranostic platforms. Current magnetic upconversion luminescent nanocomposites generally suffer from relatively large size and/or low magnetization, which might induce unsatisfactory colloidal stability, reticuloendothelial system clearance, and limit their applications in biolabeling, sensing, imaging, bioseparation, magnetic targeting, and so on. Herein, we constructed multimagnetic-beads-embedded Fe3O4/NaYF4: Yb, Er nanocomposites to overcome these problems. Polyelectrolyte was introduced as an organic intermediate layer to offset the crystal lattice mismatch between Fe3O4 and NaYF4: Yb, Er. It also acted as the ligand to direct the growth of NaYF4: Yb, Er on the surface of Fe3O4. So-prepared nanocomposites exhibited an average size of 33.8 nm, much smaller than those with magnetic nanoparticle clusters as the core. The saturation magnet...
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