Abstract
То evaluate the incidence of different types of organic abnormalities occurring in premature sexual development (PSD) of central genesis and to study a role of magnetic resonance imaging (MRI) in the diagnosis of PSD, MRI was used in 33 patients with a clinically established diagnosis of true (gonadotropin-dependent) PSD of central genesis. Among the examined children with PSD, hypothalamic hamartoma was detected in 27.3%) of the patients; there were no MRI data suggesting hypothalamopituitary abnormalities in 72.7%o. On the MRI images, a hypothalamic hamartoma appeared as a round or oval mass having a well -defined outlines, a homogeneous structure, 3 to 15 mm in size, which is located in the projection of mamillary bodies or retrochiasmally. Patients with PSD were found to have an increased volume of the adenohypophysis mainly due to the vertical size as compared with a group of healthy children of the same age.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call