Magnetic Resonance Image under the Low-Rank Matrix Denoising Algorithm in Evaluating the Efficacy of Neoadjuvant Chemo-Radiotherapy for Rectal Cancer

Abstract

This study was to explore the application value of magnetic resonance imaging (MRI) images obtained by low-rank matrix recovery algorithm (LRMR algorithm) in evaluating the curative effect of rectal cancer patients receiving the neoadjuvant chemo-radiotherapy (nCRT). In this study, an image denoising model was designed based on the LRMR algorithm, the original low-rank data matrix was recovered from the error, and the low-rank matrix was restored by solving the optimal kernel norm, so as to effectively separate the image data information and the interference noise. In addition, the model was applied to 60 patients with rectal cancer who received nCRT to extract the texture parameters and lesion-related data from the MRI images. The results showed that the MRI images optimized by LRMR algorithm were clearer than the original images, contained less excess noise, and had improved imaging accuracy and image quality. The results of typical cases suggested that the front of the rectal wall membrane of a patient in the T-downstage group was not smooth before treatment, the internal angiography was blurred, and the wall membrane was thickened, but the wall membrane became thinner after treatment, the highest position was reduced from 1.46 cm to 0.38 cm, the average value of the apparent diffusion coefficient (ADC) increased from 0.732 × 10−3 mm2/s to 1.196 × 10−3 mm2/s, and the lesion tissue was thicker. It was found that the height, length, and ADC of the lesion after the nCRT showed statistically great difference in contrast to the values before the treatment P < 0.05 . Such results indicated that the nCRT showed obvious effects in the clinical treatment of rectal cancer. In short, the LRMR algorithm could remove the interference noise in the MRI image, and from the information about rectal cancer tumor lesions extracted from that, the height value and length value of tumor lesions in patients given neoadjuvant chemo-radiotherapy were reduced compared with those before treatment, and the apparent diffusion coefficient value was increased, indicating that neoadjuvant chemo-radiotherapy has a significant effect in the clinical treatment of rectal cancer.