Abstract
Fucan-coated magnetite (Fe3O4) nanoparticles were synthesized by the coprecipitation method and studied by Mossbauer spectroscopy and magnetic measurements. The sizes of the nanoparticles were 8–9 nm. Magnetization measurements and Mossbauer spectroscopy at 300 K revealed superparamagnetic behavior. The magnetic moment of the Fe3O4 is partly screened by the Fucan coating aggregation. When the magnetite nanoparticles are capped with oleic acid or fucan, reduced particle-particle interaction is observed by Mossbauer and TEM studies. The antitumoral activity of the fucan-coated nanoparticles were tested in Sarcoma 180, showing an effective reduction of the tumor size.
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