Abstract
Traditional knowledge and ethno-botanical use of plants have been widely acknowledged all over the world. Certain people of India, using whole plant of Euphorbia hirta L . as an effective remedy for varities of diseasese. The documentation of traditional knowledge from eastern Uttar pardesh area reveals that it is highly widely used in Ayurveda . Pharmacological and physico- chemical details of E.hirta not available in authentic litrature including API (Ayurvedic Pharmacopea of India) So the validation and standardisation of whole plant of Euphorbia hirta . was carried out to establish its macro- and microscopical standards, physicochemical parameters, preliminary phytochemical investigation and TLC profiles to evaluate the characters of the plant. Macroscopic characters of E. hirta leaves shows composition of leaf is simple with dark green color about 2-6cm. long in size, T.S. of the leaf revealed the presence of stomata, upper and lower epidermis, vascular bundle. Powder characteristics revealed the presence of starch gran-ules, covering trichomes. The various diagnostic characteristic of leaf powder was coarse, dark green, which revealed the presence of lignified xylem vessel,anomocytic type of sto-mata, Physicochemical parameters were also evaluated. Preliminary phytochemical analysis indicated a high percentage of quercetine and flavonoids and this may be one of the reasons behind the anti diabatic and hepatoprotective activity of this plant. The above parameters, which are being reported for the first time in this plant, are significant towards establishing the pharmacognostic standards for future identification and authentication of genuine plant material used Ayurveda for various diaeases in eastern UP.
Highlights
As a result of the side effects associated with synthetic drugs, people started looking back at the ancient healing systems like Ayurveda, Siddha and Unani
1 The Eastern Uttar Pradesh is using many plants by by Ayurvedic practicner for their health care and day to day ailments but many of them are not yet scientifically validated. This plant called dudhi as an effective remedy for various ailments. It is identified as Euphorbia hirta Linn. of the family Euphorbiaceae. , they prefer methanolic extract of whole plant of E. hirta Linn.as a remedy for various disease[2,3] As far as the available literature is concerned, this plant has not yet been scientifically validated
Powder characteristics revealed the presence of starch gran-ules, sclariform vessels, covering trichomes, lignified fibres, pericyclic fibres, epidermial cells with trichomes.The various diagnostic characteristic of leaf powder was coarse, dark green, odourless, with bitter test which revealed the presence of lignified xylem vessel,anomocytic type of sto-mata, epidermal cells with stomata, pericyclic fibers, scaliform vessels and trichomes.The quantitative determination of some pharmacognostic parameters is useful for setting standard for crude drugs the vein islet, vein termination and other parameters determined in the quantitative microscopy are relatively constant for the plants and can be used to differentiated closely www.ssjournals.com related spe-cies
Summary
As a result of the side effects associated with synthetic drugs, people started looking back at the ancient healing systems like Ayurveda, Siddha and Unani. 1 The Eastern Uttar Pradesh is using many plants by by Ayurvedic practicner for their health care and day to day ailments but many of them are not yet scientifically validated. This plant called dudhi as an effective remedy for various ailments. It is identified as Euphorbia hirta Linn. They prefer methanolic extract of whole plant of E. hirta Linn.as a remedy for various disease[2,3] As far as the available literature is concerned, this plant has not yet been scientifically validated. Its distributed throughout the hotter parts of India and Australia, frequently found in waste places along the roadsides. 4 Study, pharmacognostic standardisation of E. hirta Linn. was carried out to establish its macro- and microscopical
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