Abstract

A water-soluble chitosan derivative, namely, N-succinylchitosan (NS-Chit), was used as a matrix for the formation of silver nanoparticles (AgNP) by metal ion re duction under influence of microwave irradiation in the presence of D-glucose as a reducing agent. The electron plasmon resonance spectra (λmax = 410 nm) obtained for the irradiated solutions were typical of spherical silver nanoparticles. The in vitro tests confirmed a high bactericidal activity of the colloidal solution containing AgNP in a NS-Chit polymer matrix against strains of grampositive bacteria, namely, Bacillus subtillus (ATCC 6633), B. coagulans (429), and Staphylococcus aureus (ATCC 21027).

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