Abstract
The possible role of lysosomal enzymes in adenovirus uncoating has been investigated. Lysosomes were isolated from guinea pig liver, and a total lysosomal extract was in vitro assayed on adenovirus particles and its structural antigens. Adenovirus capsid and morphological subunits were insensitive to lysosomal enzymes. These results suggest that the factor responsible for adenovirus uncoating is not located within lysosomes and support the assumption by other investigators that this uncoating process occurs in close vicinity to the plasma membrane.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
