Abstract
The effect of gravity on human lymphocytes in-vitro has been extensively studied by our team in true microgravity in space /1-3/, in simulated lowgravity in the clinostat /4,5/ and in hypergravity in the centrifuge /5-7/. Lymphocytes are easily purified from peripheral blood and can be ictivated either chemically or by exposure to mitogens in culture. Thereby, cells start to proliferate, T—lymphocytes secrete lymphokines (IL-2, IL-3, IL—4 as well as interferon). The mechanism of the in-vitro activation is analogous to that occurring in—vivo when the immune system is challenged by antigens.
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More From: Advances in space research : the official journal of the Committee on Space Research (COSPAR)
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