Abstract

(1→6)-2,5-Anhydro-3,4-di- O-methyl- d-glucitol (2a) and (1→6)-2,5-anhydro- d-glucitol (2c) and its sulfated derivative (2d) were synthesized and their biological activities were evaluated in regards to the effects on murine lymphocytes. The polymers showed different effects on the lymphocytes depending on the substituent groups. The sulfated polymer (2d) induced mitogenic activities, and specifically activated the CD4(-)CD8(-) subset of lymphocytes.

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