Abstract
Summary A procedure for vascular perfusion of rat upper jejunum with heparinized homologous blood is described. When bicarbonate Ringer solution was placed in the lumen of the intestine, net water absorption was demonstrated by a positive V-A difference (venous outflow rate > arterial inflow rate) and lymph flow. The sum of V-A difference and lymph flow was found to be equal to the rate of water disappearance from the lumen of intestine. When an unabsorbable salt solution (MgSO 4 ) was placed in the lumen, the V-A difference was either zero or negative and lymph flow was nil. Lymph flow was small at low venous pressure but increased at high venous pressure. The change of arterial pressure between 50 and 100 mm Hg exerted no significant effect on lymph flow. The rate of water transport into the venous system as well as that of the total net water transport were reduced at high venous pressure. The percentage transport of water by the lymphatic system increased with the increase of venous pressure and the reverse was the case for the percentage transport by the venous system. At very low venous pressure (0 to 5 mm Hg), lymph flow accounted for 10 to 25% of net water transport but, at high venous pressure (above 20 mm Hg), net water transport was entirely by way of the lymphatic system.
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