Abstract
Background Usually, classic Kaposi's sarcoma (KS) is clinically characterized by maculae, plaques and nodules and histologically by a proliferation of irregularly-shaped blood vessels, spindle cells and extravasated erythrocytes. The course is indolent. Very rarely, cases have been reported in which malignant transformation occurred with subsequent visceral diffusion.Observations A case of classic KS in an 82-year-old man is reported. Clinically, the lesion appeared to be a nodule which grew rapidly to become an exophytic tumour mass. Histopathologically, it was characterized at the beginning by a lymphangioma-like pattern with subsequent frank anaplasia. The diagnosis of KS was based on lymph node examination which showed typical features. The patient died after 1 year.Conclusions Taking into account these unusual patterns we emphasize their importance in the differential diagnosis of KS from other angiomatous and anaplastic lesions.
Published Version
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