Abstract
A new lupane type triterpene (1), together with betulinic acid (2), friedelin (3), aristolochic acid I (4), alpinumisoflavone (5) and 4’-O-methylepinumisoflavone (6) have been isolated from the leaves of Thecacoris annobonea. The structure of the new compound was elucidated on the basis of 1 and 2D NMR experiments. The isolated compounds were evaluated for their phytotoxicity and antimicrobial activity. 1 exhibited significant antimicrobial activity at 30 μg/ml and compounds 1, 2, 3, 4, 5 and 6 inhibited root growth lettuce at 100 μg/ml.
Highlights
Thecacoris annobonea (Euphorbiacea) is a small tree or shrub growing in South and South-West provinces of Cameroon
In our previous study on the genus Thecacoris, aristolochic acid, vanillic acid and friedelin which showed good antimicrobial activities were isolated from the stem bark of T. annobonea [2] and, diterpenoids and triterpenoids were isolated from the twigs of T. batesii [1]
The extract was submitted to repeated column chromatography and preparative TLC to afford betulinic acid, friedelin, aristolochic acid I, alpinumisoflavone, 4’-O-methylepinumisoflavone as well as one new lupane type triterpene (1)
Summary
Thecacoris annobonea (Euphorbiacea) is a small tree or shrub growing in South and South-West provinces of Cameroon. The present paper deals with the isolation and structural elucidation of one new lupane type triterpene and demonstrates its phytotoxicity and antimicrobial activity together with the other isolated known compounds. The extract was submitted to repeated column chromatography and preparative TLC to afford betulinic acid, friedelin, aristolochic acid I, alpinumisoflavone, 4’-O-methylepinumisoflavone as well as one new lupane type triterpene (1).
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
