Abstract

PurposeThe purpose of this study was to evaluate the usefulness of single-shot dual-energy subtraction (DES) method using a flat-panel detector for lung cancer screeningMaterials and methodsThe subjects were 13,315 residents (5801 males and 7514 females) aged 50 years or older (50–97 years, with an intermediate value of 68 years) who underwent lung cancer screening for a period of 1 year and 6 months from January 2019 to June 2020. We investigated whether the number of lung cancers detected, the detection rate, and the rate of required scrutiny changed, when DES images were added to the judgment based on conventional chest radiography.ResultsWhen DES images were added, the number and percentage of cancer detection increased from 16 (0.12%) to 23 (0.17%) (P < 0.05). Five of the newly detected 7 lung cancers were in the early stages of resectable cancer. The rate of participants requiring scrutiny increased slightly from 1.1 to 1.3%.ConclusionDES method improved the detection of lung cancer in screening. The increase in the percentage of participants requiring scrutiny was negligible.

Highlights

  • The effectiveness of lung cancer screening by chest radiography is considered to be limited [1], and some researches on lung cancer screening by low-dose CT are ongoing [2, 3]

  • The detection of lung cancer by chest radiography is not sufficient and the detection rate has been reported to be 70–80% [4, 5]. This is mostly due to the fact that the ribs and clavicles overlap the lungs on chest radiography, making it difficult to detect nodular shadows [6]

  • We examined whether the presence or absence of dual-energy subtraction (DES) images changed the percentage of participants who required scrutiny and the number of cancers detected

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Summary

Introduction

The effectiveness of lung cancer screening by chest radiography is considered to be limited [1], and some researches on lung cancer screening by low-dose CT are ongoing [2, 3]. The detection of lung cancer by chest radiography is not sufficient and the detection rate has been reported to be 70–80% [4, 5]. This is mostly due to the fact that the ribs and clavicles overlap the lungs on chest radiography, making it difficult to detect nodular shadows [6]. This study was conducted on residents who underwent lung cancer screening for a period of 1 year and 6 months from January 2019 to June 2020. A total of 13,315 residents (5801 males and 7514 females) aged 50 years and older

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