Abstract
The extent of tumor necrosis can be determined by the knowledge of the penetration depth of the light through tissue. So, we must determine the effective penetration depth `(delta) ' during treatment, depth at which the incident light intensity is reduced to 36.6%. Light transmission measurements through tissues is the experimental model usually used as a reference method to estimate the value of (delta) . In order to achieve subsequently on line and in situ light dosimetry during PDT, light backscattering has been studied in different concentrations of blue ink and intralipid-20%. All parameters which would influence the value of the back-attenuation coefficient (Sigma) <SUB>ba</SUB> have been reviewed separately. The results of transmission and backscattering measurements are compared. A correlation function `R' between (Sigma) <SUB>eff</SUB> and (Sigma) <SUB>ba</SUB> can be deduced, the knowledge of R allows us to determine the effective light penetration depth in tissue through backscattering measurement.
Published Version
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