Abstract

On a hog farm in Miyazaki Prefecture a home-produced primiparous sow gave birth to 9 piglets, fiveof which died within 24 hours after birth, discharging red bloody feces. Autopsy revealed hemorrhagic enteritis in the small intestine, especially in the jejunum. Necrosis, hemorrhage, and emphysema were seen in villi, submucosa, and tunica propria mucosae of the jejunum.After bacterial culture a small amount of Clostridium perfringens was isolated from parenchymatous organs and 109-1010 organisms jg of this species were from the jejunal contents in dead piglets. When 4 isolated strains were examined for toxin type, 2 strains were of type A organisms and another two of type C ones. The 4 strains showed an a-toxin value of more than 3.The isolates were highly Sensitive to penicillin, aminobenzyl penicillin, and bacitracin, but not at all to streptomycin, kanamycin, or colistin. Finally, this case was diagnosed as enterotoxemia caused by mixed infection with type A and C organisms of a high virulent strain of C. perfringens.

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