Abstract
Four hundred three (20%) out of 2012 piglets died during the January-March period of 1990 on a pig farm in Chiba Prefecture. The disease almost exclusively affected newborn pigletswithin the 1st week of life, especially in the first 3 days. Main clinical signs were mucohemorrhagic diarrhea and dehydration. Autopsy revealed hemorrhagic enteritis in the small intestine, particulary in the jejunum, showing necrosis and hemorrhage. Clostridium perfringens was isolated from all the intestines tested on the order of 107 to108 CFU/g. Toxinsdetected in the intestinal contents of three piglets and in bacterial cultures were of C. perfringens type C. The isolates were highly sensitive to penicillin and ampicillin.
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