Abstract
ObjectiveTo compare plasma lipids and lipoproteins concentrations in newborns with intrauterine growth restriction and alterations of umbilical artery end-diastolic velocity. Material and methodsA study was conducted on pregnant women with a diagnosis of intrauterine growth restriction who attended at Hospital Central Dr. Urquinaona, Maracaibo, Venezuela. The cases were divided into, reversed umbilical artery end-diastolic velocity (group A), absent umbilical artery end-diastolic velocity (group B), and umbilical artery end-diastolic velocity present and positive (groupC). Plasma concentrations of cholesterol, triglycerides, and low- and high-density lipoproteins were also measured in newborns. ResultsReversed umbilical artery end-diastolic velocity was present in 33 cases, with 71 cases of absent umbilical artery end-diastolic velocity, and 146 cases with umbilical artery end-diastolic velocity present. The newborns in groups A and B had significantly higher plasma concentrations of cholesterol and triglycerides compared with group C (p<.05). High-density lipoproteins were significantly lower in group A and B compared with group C (p<.05). There were no significant differences found in low-density lipoproteins between the three groups (p>.05). ConclusionNewborns with intrauterine growth restriction and absent or reversed umbilical artery end-diastolic velocity showed significant alterations in plasma lipids and lipoproteins concentrations.
Published Version
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