Abstract
In the presence of Me3SiCl, Ti(O-i-Pr)4/Mg and CpTiCl3/Mg reagents effectively catalyzed the deprotection of allyloxycarbonyl (alloc)- and propargyloxycarbonyl (poc)-protected amines in THF at around room temperature to produce parent amines in good yields. Alloc- and poc-protected secondary amines were smoothly deprotected to parent amines by a reaction catalyzed by a Ti(O-i-Pr)4/Me3SiCl/Mg reagent. The deprotection of alloc- and poc-protected primary amines was successfully catalyzed by a CpTiCl3/Me3SiCl/Mg reagent.
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