Abstract

Eleven phytoecdysteroids have been isolated and identified from the low polarity fractions of Serratula coronata juice by a combination of column chromatography and HLPC. Four of them are new, i.e. ecdysone 22-acetate 7, (25S)-inokosterone 26-acetate 9, 20,22-O-(R-ethylidene)-20-hydroxyecdysone 10 and 20,22-O-(R-ethylidene)-ajugasterone C 11. The biological activity of these new ecdysteroids in the Drosophila melanogaster BII cell bioassay is reported.

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