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Abstract
Natural ecdysteroids isolated from Serratula coronata L., including 20-hydroxyecdysone (20-HE), 25-S-inokosterone, and ecdysone, did not exhibit antimicrobial activity with respect to most standard test microbe cultures. The introduction of the acetyl group into the 20-HE molecule significantly increased the antibacterial activity with respect to microbes inducing inflammatory and purulent processes. Acyl derivatives of 20-hydroxyecdysone can be suggested for use in wound-healing compositions
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