Abstract
In the process of development and practical application, local anesthesia met many contraindications and limitations. The latter were based both on clinical observations and experiments, as well as on a priori judgments. In particular, the use of local anesthesia in acute inflammatory and purulent processes was considered inadmissible. There are still strong fears that in these conditions, local anesthesia threatens with dissemination of microbes and their toxins (sepsis, pyemiak).
Published Version
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