Loopy Orthogonal Signal Correction Scatter Correction in Non-Invasive Blood Glucose

Abstract

Spectroscopy is the study of matter based on light, sound, or particles emitted, absorbed, or reflected as well as the study of methods for generating and analyzing spectra. The spectrum has systematic diversity, namely the presence of light scattering and differences in the size of objects. The spectroscopic output allows for scattering shifts, because the same object measured several times does not exactly produce the same spectrum. Problems found in the spectrum can be overcome by pre-processing the data, namely the scatter correction method. Scatter correction is used to reduce the physical properties in the spectrum so that the information obtained is relatively the same for each spectrum, produces good estimates, and can be interpreted well. One of the spectroscopic tools that utilize infrared light is a non-invasive blood glucose level measuring device. The output of the tool is the time domain and intensity spectrum. Each object from the resulting spectrum still has noise, so scatter correction can be applied to this data. The purpose of this study was to perform a loopy Orthogonal Signal Correction (OSC) scatter correction method on time domain spectrum data on intensity on a non-invasive blood glucose level measuring device. The OSC method uses the concept of orthogonality to the mean by drawing the intensity value, weighting it, calculating the vector loading and then making corrections to the initial intensity. Based on the analysis, the loopy OSC method is better than OSC because the convergence is more accurate, the mean difference is smaller, the variance is smaller and the value converges on all the values tested. Based on exploration and the average difference, the loopy OSC method is better able to form the same pattern for each replication. This also shows that an object that is measured repeatedly has been able to be identified as the same object.