Abstract
BackgroundUncemented allograft prosthesis composite (APC) has been applied for tumorous bone defect reconstruction in the proximal femur. However, the long-term results are rarely reported. This study aimed to evaluate long-term outcomes of uncemented APC.MethodsEighteen patients who received uncemented APC reconstruction in the proximal femur after tumor resections were retrospectively reviewed.ResultsThe average resection length was 110 mm (80–154) and the average follow-up was 106.7 months (65–141). Bone union achieved in all patients with an average duration of 7.6 months (5–10). The average HHS, MSTS score and gluteus medius strength at one-year follow-up were 88.0 (80–94), 25.2 (22–28) and 4 (3–5), respectively. While at the last follow-up, the HHS, MSTS score and gluteus medius strength were 83.0 (48–100), 24.0 (10–30) and 4 (2–5), respectively. Five intraoperative fractures were fixed with cerclage wires. Two postoperative periprosthetic and prosthetic fractures received a revision. Three local recurrent patients received a secondary surgery. One of these three lung metastatic patients underwent lung metastatic tumor resection. Another two patients were diagnosed with both bone and lung metastases, only one of them underwent amputation. Two greater trochanteric fractures received no treatment. There were10 severe, 3 moderate and 5 mild allograft resorptions without treatment.ConclusionUncemented APC is a reliable reconstruction for neoplastic bone defect of the proximal femur, especially for the young patient who expected long-life expectancy and good function. Though allograft resorption and trochanteric fracture are the common complications, they seem no effect on the function.
Highlights
Uncemented allograft prosthesis composite (APC) has been applied for tumorous bone defect reconstruction in the proximal femur
Since the 1980s, it has been used for the reconstruction of neoplastic bone defects and revision hip arthroplasty (RHA), especially when the circumferential femoral bone defects are greater than 3 cm in length [12,13,14]
Bone union at the allograft-host junction achieved in all patients on an average of 7.6 months (5–10) without a delayed union
Summary
Uncemented allograft prosthesis composite (APC) has been applied for tumorous bone defect reconstruction in the proximal femur. This study aimed to evaluate long-term outcomes of uncemented APC. The cemented or partial cemented APC hold a high rate of nonunion in previous studies, up to 23% [1, 14, 17,18,19,20,21]. Revision of cemented or partial cemented APC needs to remove the allograft, which makes the advantage of restoring bone stock no longer exist [14, 21, 22]
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