Abstract
The biological half-life (Tœ) of 75Se determined with whole body counting varied from 37 to 68 days in four children each suffering from one of the following diseases: Congenital muscular dystrophy (M.D), limb girdle type of M.D., nemaline myopathy, and Werdnig-Hoffmann disease (infantile spinal muscular atrophy) the T œ values of two boys with severe tetraplegy from 81 to 84 days. The Tœ values of the patients with progressive muscular diseases did not differ from those found in the patients with Duchenne type of M.D. in an earlier investigation, but they were significantly smaller than those of healthy controls.
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