Long-term oncological results of radical prostatectomy in patients with localized prostate cancer

Abstract

The objective: was to perform a comparative analysis of the direct results of a pathomorphological study of the organo-complex removed from radical prostatectomy and the frequency of biochemical recurrence (BCR) in patients with localized prostate cancer (RPP) in the performance of a retropubic radical prostatectomy (PRPD) and endoscopic radical prostatectomy (EDGE) clinics.Materials and methods. The clinical study involved 360 patients who had undergone PRPE or ESRD in the clinic of the Institute of Urology of the National Academy of Medical Sciences of Ukraine during 2012-2016. The patients were divided into two groups. Group 1 (n = 99) – patients who were operated in the clinic in the volume of PRPE from 2012 to 2016 inclusive, who have localized PCa, or the status of pT0. Group 2 (n=261) – patients who were operated in the clinic in the volume of ERSE from 2012 to 2016 inclusive, who have been diagnosed with localized PCa, or the status of pT0.Results. PRP and ESRP, which are performed by patients with localized PCa in a clinic for a five-year period, show comparable oncological outcomes.The conclusion. The implementation of multifocal biopsy and radical prostatectomy (RPE) in the same clinic promotes better comparability, reproducibility and greater consistency of the obtained morphological data. It is necessary to introduce a routine immunohistochemical study of biopsy material for further clinical practice to confirm the diagnosis of prostate cancer before performing RP.