Long-term dietary supplementation with natural honey does not predispose growing male rats to metabolic syndrome

Abdulwahid Ajibola,Kennedy H Erlwanger,Joseph P Chamunorwa

doi:10.1186/1753-6561-6-s3-p3

Abstract

Background Metabolic syndrome (MetS) is a condition characterized by abdominal obesity, hyperglycaemia, hypertension and dyslipidaemia, and thus increased susceptibility to diabetes, kidney and heart diseases [1]. The modern human diet contains refined sugars mainly fructose, which is culpable in the global incidence and prevalence of MetS in adults and children [2,3]. We investigated the effects of two dietary sources of fructose, natural honey (NH) and golden syrup (GS) on metabolism in growing animal models (Sprague Dawley rats) fed from neonatal age. Methodology

Highlights

Metabolic syndrome (MetS) is a condition characterized by abdominal obesity, hyperglycaemia, hypertension and dyslipidaemia, and increased susceptibility to diabetes, kidney and heart diseases [1]
natural honey (NH) or golden syrup (GS) was mixed with rat chow as low (20%) or high, 50%, while 20% (v/w) tap water was added to the control diet
The rats were subjected to an oral glucose tolerance test (OGTT) 48hours before the end of the 13-week study

Summary

Introduction

Metabolic syndrome (MetS) is a condition characterized by abdominal obesity, hyperglycaemia, hypertension and dyslipidaemia, and increased susceptibility to diabetes, kidney and heart diseases [1]. The modern human diet contains refined sugars mainly fructose, which is culpable in the global incidence and prevalence of MetS in adults and children [2,3]. We investigated the effects of two dietary sources of fructose, natural honey (NH) and golden syrup (GS) on metabolism in growing animal models (Sprague Dawley rats) fed from neonatal age

Methods

Results

Conclusion