Abstract
In the present study the possibility of provoking an irreversible blockade of P 2-receptors in vivo by photolyzing ANAPP 3 was investigated. ANAPP 3 administered as an intraarterial infusion produced a short-lived blockade of P 2-receptor mediated contractions of cat urinary bladders in situ . However, irradiation of the bladders with visible light during the infusion of ANAPP 3 resulted in a blockade of the response for at least 120 minutes. Thus, photoactivation of ANAPP 3 in vivo produced an essentially irreversible blockade of P 2-purinergic receptors.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
